Rilpivirine

C22H18N6CAS 500287-72-9366.43 g/mol

NNNHNNNH
AlkeneNitrileSecondary amine

Properties

Molecular formula
C22H18N6
Molar mass
366.43 g/mol
Exact mass
366.1593 Da
Melting point
245 °C
logP
4.41Crippen estimate
Polar surface area
100.7 Ų
H-bond donors / acceptors
2 / 5
Rotatable bonds
4
Double bonds
EE/Z, in SMILES order

Identifiers

CAS number
500287-72-9
SMILES
Cc1cc(/C=C/C#N)cc(C)c1N=c1ccnc(Nc2ccc(C#N)cc2)[nH]1
InChIKey
YIBOMRUWOWDFLG-ONEGZZNKSA-N
InChI
InChI=1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)/b4-3+

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Names and synonyms

5 names
  • Benzonitrile, 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]-
  • 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
  • R 278474
  • TMC 278
  • Rekambys

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Similar compounds

Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds

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