Estradiol
Properties
- Molecular formula
- C18H24O2
- Molar mass
- 272.39 g/mol
- Exact mass
- 272.1776 Da
- Melting point
- 173–179 °C
- Water solubility
- 3.9 mg/L (27 °C)
- logP
- 3.61Crippen estimate
- Polar surface area
- 40.5 Ų
- H-bond donors / acceptors
- 2 / 2
- Rotatable bonds
- 0
- Stereocentres
- S, S, R, S, Sin SMILES atom order
Hazards
Danger
- H350 May cause cancer39.6% of notifiers
- H351 Suspected of causing cancer57.9% of notifiers
- H360 May damage fertility or the unborn child82.4% of notifiers
- H360FD May damage fertility; May damage the unborn child11.9% of notifiers
- H362 May cause harm to breast-fed children32.7% of notifiers
- H372 Causes damage to organs through prolonged or repeated exposure34.6% of notifiers
- H400 Very toxic to aquatic life30.8% of notifiers
- H410 Very toxic to aquatic life with long lasting effects36.5% of notifiers
Aggregated from 159 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.
Precautionary statements
P203, P260, P263, P264, P270, P273, P280, P318, P319, P391, P405, P501
Identifiers
CAS number
50-28-2SMILES
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2OInChIKey
VOXZDWNPVJITMN-ZBRFXRBCSA-NInChI
InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1Weigh it out
Type any one amount. The others follow from the molar mass.
Names and synonyms
116 names · show all
- Estra-1,3,5(10)-triene-3,17-diol (17β)-
- (17β)-Estra-1,3,5(10)-triene-3,17-diol
- Altrad
- Bardiol
- Beta-estradiol
- Dihydrofollicular hormone
- Dihydrofolliculin
- Dihydromenformon
- Dihydrotheelin
- Dihydroxyestrin
- Diogyn
- Diogynets
- 3,17-Epidihydroxyestratriene
- Estraldine
- Dimenformon
- Estrovite
- Femestral
- Femogen
- Gynergon
- Gynoestryl
- Lamdiol
- Macrodiol
- Nordicol
- Oestergon
- Oestradiol
- Oestroglandol
- Ovahormon
- Ovasterol
- Ovastevol
- Ovocyclin
- Primofol
- Profoliol
- Progynon
- Progynon DH
- Syndiol
- Theelin, dihydro-
- Estra-1,3,5(10)-triene-3,17β-diol
- Ginosedol
- Estra-1,3,5(10)-triene-3,17-diol, (17β)-
- β-Estradiol
- (+)-3,17β-Estradiol
- Oestra-1,3,5(10)-triene-3,17β-diol
- 3,17β-Dihydroxyestra-1,3,5(10)-triene
- 3,17β-Estradiol
- Perlatanol
- Aquadiol
- Follicyclin
- Corpagen
- 17β-Oestradiol
- Estradiol-17β
- Estrace
- Compudose
- Estraderm
- Compudose 365
- E 2
- Compudose 200
- Estrogel
- Estraderm TTS
- Oestrogel
- Menorest
- Systen
- Evorel
- Climaderm
- 13β-Methyl-1,3,5(10)-gonatriene-3,17β-ol
- Estraderm TTS 50
- Epiestriol 50
- Estroclim 50
- Dermestril
- Climara
- Oesclim
- 17β-Estradiol
- Encore
- Aerodiol
- Divigel
- Sandrena 1
- Vagifem
- Gelestra
- Estraderm TTS 100
- Zumenon
- Vivelle
- NSC 9895
- Profoliol B
- Ovocylin
- Estring vaginal ring
- Estroclim
- Estradot
- Femanest
- Estrogel HBF
- Absorlent matrix
- FemSeven
- Estrapatch
- Estraderm MX
- Alora
- Estasorb
- Estredox
- Estreva
- Bio-E gel
- Benzogynestry
- Estropause
- Menostar
- Evamist
- Zesteem
- Compudose 400
- Compudose 100
- Vivelle-dot
- Sprediol
- Elestrim
- Estring
- Fempatch
- Gynodiol
- Innofem
- Destradiol
- 17β-Estradiol E2
- TX 004HR
- IMVEXXY
- (8R,9S,13S,14S,17S)-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Work with Estradiol
Stereoisomers, salts and isotopologues
The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.
Similar compounds
Estriol50-27-168 % similar
Estradiol 17-acetate1743-60-864 % similar
2-Methoxyestradiol362-07-264 % similar
Estradiol cypionate313-06-460 % similar
Estradiol benzoate50-50-060 % similar
Estra-1,3,5(10),16-tetraen-3-ol1150-90-958 % similar
Estradiol valerate979-32-858 % similar
Estrone53-16-757 % similar
Tanimoto similarity of circular fingerprints over the whole catalogue.