Cyclophosphamide
Properties
- Molecular formula
- C7H15Cl2N2O2P
- Molar mass
- 261.08 g/mol
- Exact mass
- 260.0248 Da
- Density
- 1.48 g/mL
- Melting point
- 49.5–53 °C
- Boiling point
- 336 °C
- Flash point
- 113 °C (closed cup)
- Water solubility
- 10–50 g/L (22.8 °C)
- logP
- 1.88Crippen estimate
- Polar surface area
- 41.6 Ų
- H-bond donors / acceptors
- 1 / 2
- Rotatable bonds
- 5
Hazards
Danger
- H301 Toxic if swallowed63.2% of notifiers
- H302 Harmful if swallowed35.3% of notifiers
- H318 Causes serious eye damage36.8% of notifiers
- H340 May cause genetic defects95.6% of notifiers
- H350 May cause cancer98.5% of notifiers
- H360 May damage fertility or the unborn child94.1% of notifiers
- H372 Causes damage to organs through prolonged or repeated exposure36.8% of notifiers
Aggregated from 68 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.
Precautionary statements
P203, P260, P264, P264+P265, P270, P280, P301+P316, P301+P317, P305+P354+P338, P317, P318, P319, P321, P330, P405, P501
Identifiers
CAS number
50-18-0SMILES
O=P1(N(CCCl)CCCl)NCCCO1InChIKey
CMSMOCZEIVJLDB-UHFFFAOYSA-NInChI
InChI=1S/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)Weigh it out
Type any one amount. The others follow from the molar mass and density.
Names and synonyms
56 names · show all
- Revimmune
- 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide
- 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide
- B 518
- NSC 26271
- Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
- N,N-Bis(2-chloroethyl)-N′,O-propylenephosphoric acid ester diamide
- N,N-Bis(β-chloroethyl)-N′,O-trimethylenephosphoric acid ester diamide
- Cyclophosphamid
- Cyclophosphan
- Cyclophosphane
- Cytoxan
- Endoxan
- Genoxal
- Clafen
- Cytophosphan
- Claphene
- Asta B 518
- 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide
- Procytox
- Sendoxan
- (±)-Cyclophosphamide
- (RS)-Cyclophosphamide
- Cyclostin
- Cycloblastin
- Neosar
- Neosar (antineoplastic)
- Endoxanal
- CP
- Senduxan
- Zyklophosphamid
- NCI C04900
- Endoxan R
- Endoxan-asta
- Endoxana
- Mitoxan
- Endoxane
- Enduxan
- CB 4564
- SK 20501
- CPA
- CY
- Hexadrin
- Cyclophosphamidum
- CTX
- Semdoxan
- Ledoxan
- Cytophosphane
- Eldamide
- Neophos
- Cyphos
- Cydoxan
- Cycrame
- Oncomide
- Cyclocel
- Cycloxan
Work with Cyclophosphamide
Predict the NMR spectrum1H and 13C shifts with multiplicities
Make a solutionWhat to weigh for any molarity and volume
Check drug-likenessLipinski, Veber and lead-likeness
Boiling point under vacuumAt any pressure, from its normal boiling point
Isotope patternExact mass and the mass spectrum pattern
Stereoisomers, salts and isotopologues
The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.
Similar compounds
Tanimoto similarity of circular fingerprints over the whole catalogue.