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Eltrombopag

C25H22N4O4CAS 496775-61-2442.48 g/mol

Open in Covalent MOL file
NNONHNOHOHO
AmideCarboxylic acidHydrazoneLactamPhenolSecondary amine

Properties

Molecular formula
C25H22N4O4
Molar mass
442.48 g/mol
Exact mass
442.1641 Da
logP
4.56Crippen estimate
Polar surface area
114.6 Ų
H-bond donors / acceptors
3 / 6
Rotatable bonds
5

Hazards

No GHS classification is on file for this compound. That is not evidence that it is harmless. Search the SDS library

Identifiers

CAS number
496775-61-2
SMILES
CC1=NN(c2ccc(C)c(C)c2)C(=O)/C1=NNc1cccc(-c2cccc(C(=O)O)c2)c1O
InChIKey
XDXWLKQMMKQXPV-QYQHSDTDSA-N
InChI
InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)/b27-22-

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Names and synonyms

4 names
  • [1,1′-Biphenyl]-3-carboxylic acid, 3′-[(2Z)-2-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2′-hydroxy-
  • [1,1′-Biphenyl]-3-carboxylic acid, 3′-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2′-hydroxy-
  • 3′-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2′-hydroxy[1,1′-biphenyl]-3-carboxylic acid
  • SB 497115

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Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Eltrombopag olamine496775-62-3Salt

Similar compounds

3-(3-Amino-2-hydroxyphenyl)benzoic acid376592-93-740 % similar 2′-Hydroxy-3′-nitro[1,1′-biphenyl]-3-carboxylic acid376591-95-637 % similar 2'-Chloro-biphenyl-3-carboxylic acid168619-03-237 % similar 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid328968-36-135 % similar 2′-Methoxy[1,1′-biphenyl]-3-carboxylic acid168618-47-134 % similar 3,4-Dimethylbenzoic acid619-04-534 % similar 2'-Fluorobiphenyl-3-carboxylic acid103978-23-034 % similar 3'-Methyl-biphenyl-3-carboxylic acid158619-46-633 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds

Elsewhere

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