chempirical

Naloxone hydrochloride

C19H22ClNO4CAS 357-08-4363.84 g/mol

Open in Covalent MOL file
NHOOOOHHCl
AlcoholAlkeneEtherKetonePhenolTertiary amine

Properties

Molecular formula
C19H22ClNO4
Molar mass
363.84 g/mol
Exact mass
363.1237 Da
Melting point
200–205 °C
logP
1.72Crippen estimate
Polar surface area
70.0 Ų
H-bond donors / acceptors
2 / 5
Rotatable bonds
2
Stereocentres
S, R, S, Rin SMILES atom order

Identifiers

CAS number
357-08-4
SMILES
C=CCN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(O)[C@H]1C5.Cl
InChIKey
RGPDIGOSVORSAK-STHHAXOLSA-N
InChI
InChI=1S/C19H21NO4.ClH/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11;/h2-4,14,17,21,23H,1,5-10H2;1H/t14-,17+,18+,19-;/m1./s1

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

16 names · show all
  • Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, hydrochloride (1:1), (5α)-
  • Morphinan-6-one, 17-allyl-4,5α-epoxy-3,14-dihydroxy-, hydrochloride
  • Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, hydrochloride, (5α)-
  • Normorphinone, N-allyl-7,8-dihydro-14-hydroxy-, hydrochloride
  • EN 1530
  • (-)-N-Allyl-14-hydroxynordihydromorphinone hydrochloride
  • (-)-Naloxone hydrochloride
  • Narcan
  • l-Naloxone hydrochloride
  • Nalonee
  • N-Allyldihydro-14-hydroxynormorphinone hydrochloride
  • NIH 7890
  • EN 15304
  • Narcanti
  • Nalone
  • Narcoxone

Work with Naloxone hydrochloride

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Similar compounds

Naloxone hydrochloride dihydrate51481-60-895 % similar Naltrexone hydrochloride16676-29-276 % similar Naltrexone16590-41-372 % similar Nalmefene hydrochloride58895-64-063 % similar Methylnaltrexone bromide73232-52-739 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds

Same formula

Dibenzyl L-glutamate hydrochloride4561-10-8

Elsewhere

PubChem CAS Common Chemistry NIST WebBook