Tobramycin

C₁₈H₃₇N₅O₉CAS 32986-56-4467.52 g/mol

Open in Covalent MOL file

Acetal Alcohol Ether Primary amine

Properties

Molecular formula: C₁₈H₃₇N₅O₉
Molar mass: 467.52 g/mol
Exact mass: 467.2591 Da
Melting point: 164 °C
Water solubility: freely soluble
logP: -6.30Crippen estimate
Polar surface area: 268.2 Å²
H-bond donors / acceptors: 10 / 14
Rotatable bonds: 6
Stereocentres: R, R, R, S, S, S, R, S, S, R, R, S, R, Sin SMILES atom order

Hazards

Danger

H315 Causes skin irritation46.7% of notifiers
H317 May cause an allergic skin reaction13.3% of notifiers
H319 Causes serious eye irritation40% of notifiers
H335 May cause respiratory irritation40% of notifiers
H360 May damage fertility or the unborn child20% of notifiers
H361 Suspected of damaging fertility or the unborn child13.3% of notifiers
H372 Causes damage to organs through prolonged or repeated exposure13.3% of notifiers
H400 Very toxic to aquatic life20% of notifiers
H411 Toxic to aquatic life with long lasting effects13.3% of notifiers

Aggregated from 15 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P203, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P391, P403+P233, P405, P501

Identifiers

CAS number

32986-56-4

SMILES

NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O

InChIKey

NLVFBUXFDBBNBW-PBSUHMDJSA-N

InChI

InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

20 names · show all

D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-2-deoxy-
O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-2-deoxy-D-streptamine
Nebramycin factor 6
3′-Deoxykanamycin B
Nebramycin 6
Nebramycin VI
Deoxykanamycin B
Tobramycetin
Tobramicin
Tobralex
Tobrex
Tobramaxin
NF 6
Tobradistin
Tobracin
NSC 180514
Tobramax
Tobrin
Vantobra
Tobi podhaler

Work with Tobramycin

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Tobramycin sulfate49842-07-1Salt Tobramycin sulfate79645-27-5Salt

Similar compounds

Kanamycin A59-01-882 % similar Kanamycin B4696-76-879 % similar Kanamycin sulfate25389-94-070 % similar Neomycin1404-04-257 % similar Ribostamycin sulfate53797-35-656 % similar Amikacin37517-28-555 % similar 6-Monodeoxy-6-monoamino-beta-cyclodextrine29390-67-852 % similar Arbekacin51025-85-552 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Elsewhere

PubChem CAS Common Chemistry NIST WebBook