Hydralazine hydrochloride

C₈H₉ClN₄CAS 304-20-1196.64 g/mol

Open in Covalent MOL file

Properties

Molecular formula: C₈H₉ClN₄
Molar mass: 196.64 g/mol
Exact mass: 196.0516 Da
Melting point: 273 °C (decomposes)
Water solubility: 44.2 g/L
logP: 0.76Crippen estimate
Polar surface area: 67.1 Å²
H-bond donors / acceptors: 2 / 3
Rotatable bonds: 0

Hazards

Danger

H301 Toxic if swallowed100% of notifiers
H315 Causes skin irritation93% of notifiers
H319 Causes serious eye irritation92.1% of notifiers
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled12.3% of notifiers
H335 May cause respiratory irritation81.6% of notifiers
H341 Suspected of causing genetic defects10.5% of notifiers
H371 May cause damage to organs10.5% of notifiers

Aggregated from 114 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P203, P233, P260, P261, P264, P264+P265, P270, P271, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P308+P316, P318, P319, P321, P330, P332+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, P501

Identifiers

CAS number

304-20-1

SMILES

Cl.NN=c1[nH]ncc2ccccc12

InChIKey

ZUXNZUWOTSUBMN-UHFFFAOYSA-N

InChI

InChI=1S/C8H8N4.ClH/c9-11-8-7-4-2-1-3-6(7)5-10-12-8;/h1-5H,9H2,(H,11,12);1H

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

12 names

Phthalazine, 1-hydrazinyl-, hydrochloride (1:1)
Phthalazine, 1-hydrazino-, monohydrochloride
1(2H)-Phthalazinone, hydrazone, monohydrochloride
Apresoline hydrochloride
Hydralazine monohydrochloride
1-Hydrazinophthalazine hydrochloride
1-Hydrazinophthalazine monohydrochloride
Hydralazine chloride
Lopres
(Phthalazin-1-yl)hydrazine hydrochloride
Apulon
1-Hydrazinylphthalazine hydrochloride

Work with Hydralazine hydrochloride

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Hydralazine86-54-4Free base

Similar compounds

Indazole271-44-340 % similar Dihydralazine sulfate7327-87-935 % similar α-Naphthylamine hydrochloride552-46-534 % similar 1-Naphthylhydrazine hydrochloride2243-56-333 % similar 4-Isoquinolinamine23687-25-433 % similar 1H-Pyrazolo(3,4-b)pyridine271-73-833 % similar 7-Fluoro-1H-indazole341-24-232 % similar 4-Phenyl-1H-pyrazol-5-amine57999-06-132 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Same formula

N-(4-Cyanophenyl)guanidine hydrochloride373690-68-7

Elsewhere

PubChem CAS Common Chemistry NIST WebBook