Amiloride hydrochloride

C6H9Cl2N7OCAS 2016-88-8266.09 g/mol

Open in Covalent MOL file
HClHNH2NNHONClNH2NH2N
Aryl halidePrimary amine

Properties

Molecular formula
C6H9Cl2N7O
Molar mass
266.09 g/mol
Exact mass
265.0246 Da
Melting point
293.5 °C
Water solubility
< 1 g/L (19.5 °C)
logP
-0.09Crippen estimate
Polar surface area
160.3 Ų
H-bond donors / acceptors
5 / 5
Rotatable bonds
1

Hazards

Danger
Acute Toxic (GHS06)Irritant (GHS07)

Aggregated from 128 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P264, P264+P265, P270, P273, P280, P301+P316, P302+P352, P305+P351+P338, P321, P330, P332+P317, P337+P317, P362+P364, P405, P501

Identifiers

CAS number
2016-88-8
SMILES
Cl.N=C(N)N=C(O)c1nc(Cl)c(N)nc1N
InChIKey
ACHKKGDWZVCSNH-UHFFFAOYSA-N
InChI
InChI=1S/C6H8ClN7O.ClH/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;/h(H4,8,9,13)(H4,10,11,14,15);1H

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

16 names · show all
  • 2-Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, hydrochloride (1:1)
  • Pyrazinecarboxamide, N-amidino-3,5-diamino-6-chloro-, monohydrochloride
  • Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride
  • N-Amidino-3,5-diamino-6-chloropyrazinamide hydrochloride
  • N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride
  • Amipramizide
  • Colectril
  • Amiprazide
  • Nilurid
  • Amilorid hydrochloride
  • Amipramidine
  • Guanamprazine hydrochloride
  • Midamor
  • MK-870 hydrochloride
  • 1-(3,5-Diamino-6-chloropyrazinecarboxyl)guanidine hydrochloride
  • Amiloride hydrochloride anhydrous

Work with Amiloride hydrochloride

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Stereoisomers, salts and isotopologues

The same compound in another form: other stereochemistry, a salt or hydrate, the free acid or base, or an isotope-labelled version.

Amiloride hydrochloride17440-83-4Hydrate Amiloride2609-46-3Free base

Similar compounds

Guanfacine hydrochloride29110-48-337 % similar Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate1458-01-136 % similar 2,4,5-Triamino-6-chloropyrimidine hydrochloride155824-29-631 % similar N-(Aminoiminomethyl)acetamide5699-40-131 % similar Picloram1918-02-131 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Elsewhere

PubChem CAS Common Chemistry NIST WebBook