tert-Butyldimethylsilyl chloride

C₆H₁₅ClSiCAS 18162-48-6150.72 g/mol

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Properties

Molecular formula: C₆H₁₅ClSi
Molar mass: 150.72 g/mol
Exact mass: 150.0632 Da
Density: 0.87 g/mL
Melting point: 86–88 °C (sublimes)
Boiling point: 126 °C
logP: 3.23Crippen estimate
Polar surface area: 0.0 Å²
H-bond donors / acceptors: 0 / 0
Rotatable bonds: 0

Hazards

Danger

H228 Flammable solid57.6% of notifiers
H314 Causes severe skin burns and eye damage76.3% of notifiers
H318 Causes serious eye damage29.2% of notifiers
H335 May cause respiratory irritation12.3% of notifiers
H411 Toxic to aquatic life with long lasting effects18.6% of notifiers

Aggregated from 236 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.

Precautionary statements

P210, P240, P241, P260, P261, P264, P264+P265, P271, P273, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P363, P370+P378, P391, P403+P233, P405, P501

Identifiers

CAS number

18162-48-6

SMILES

CC(C)(C)[Si](C)(C)Cl

InChIKey

BCNZYOJHNLTNEZ-UHFFFAOYSA-N

InChI

InChI=1S/C6H15ClSi/c1-6(2,3)8(4,5)7/h1-5H3

Characterization data

Calculated from the structure, in the form journals print them.

¹H NMR

Predicted ¹H NMR (400 MHz, CDCl₃) δ 0.81 (s, 9H), 0.00 (s, 6H).

¹³C NMR

Predicted ¹³C NMR (101 MHz, CDCl₃) δ 24.2, 22.8, 0.0.

[M + H]+

[M + H]+ Calcd for C6H16ClSi 151.0704

[M + Na]+

[M + Na]+ Calcd for C6H15ClNaSi 173.0524

[M − H]−

[M − H]− Calcd for C6H14ClSi 149.0559

Elemental analysis

Anal. Calcd for C6H15ClSi: C, 47.81; H, 10.03.

Weigh it out

Type any one amount. The others follow from the molar mass and density.

Names and synonyms

19 names · show all

Silane, chloro(1,1-dimethylethyl)dimethyl-
Silane, chloro-tert-butyldimethyl-
Chloro(1,1-dimethylethyl)dimethylsilane
Dimethyl-tert-butylchlorosilane
(1,1-Dimethylethyl)dimethylsilyl chloride
tert-Butyldimethylchlorosilane
Chlorodimethyl-tert-butylsilane
Chloro-tert-butyldimethylsilane
Dimethyl(1,1-dimethylethyl)chlorosilane
Dimethyl-tert-butylsilyl chloride
TBDMS chloride
tert-Butylchlorodimethylsilane
t-Butyldimethylchlorosilane
TBDMS-Cl
tert-Butyl(dimethyl)silane chloride
2-(Chlorodimethylsilyl)-2-methylpropane
TBSCl
LS 1190
2-[4-(TertButyldimethylsilanyloxy)phenyl] chloride

Safety data sheets

One stored sheet lists this compound in section 3, matched by the CAS number 18162-48-6. Each row opens the sheet with its composition and PDF.

tert-Butylchlorodimethylsilane ≤ 100 %Fisher Scientific Company · 2025-12-19

Open in the SDS library

Work with tert-Butyldimethylsilyl chloride

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Boiling point under vacuumAt any pressure, from its normal boiling point Isotope patternExact mass and the mass spectrum pattern

Similar compounds

tert-Butyltrichlorosilane18171-74-944 % similar Dichlorobis(1,1-dimethylethyl)silane18395-90-944 % similar Dimethylthexylsilyl chloride67373-56-243 % similar tert-Butyldimethylsilanol18173-64-333 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue.

All similar compounds

Same formula

Butyldimethylsilyl chloride1000-50-6 Chlorobis(1-methylethyl)silane2227-29-4 (3-Chloropropyl)trimethylsilane2344-83-4 Triethylsilyl chloride994-30-9

Elsewhere

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