chempirical

Donepezil hydrochloride

C24H30ClNO3CAS 120011-70-3415.96 g/mol

Open in Covalent MOL file
OOONHCl
EtherKetoneTertiary amine

Properties

Molecular formula
C24H30ClNO3
Molar mass
415.96 g/mol
Exact mass
415.1914 Da
Melting point
211–212 °C
logP
4.78Crippen estimate
Polar surface area
38.8 Ų
H-bond donors / acceptors
0 / 4
Rotatable bonds
6

Identifiers

CAS number
120011-70-3
SMILES
COc1cc2c(cc1OC)C(=O)C(CC1CCN(Cc3ccccc3)CC1)C2.Cl
InChIKey
XWAIAVWHZJNZQQ-UHFFFAOYSA-N
InChI
InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

12 names
  • BNAG
  • 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1)
  • 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride
  • E 2020
  • E 2020 (Pharmaceutical)
  • Aricept
  • Aricept D
  • Dopezil
  • Dorent
  • Donep
  • 1-Benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride
  • Aricept ODT

Work with Donepezil hydrochloride

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Similar compounds

Donepezil120014-06-496 % similar 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride120013-39-065 % similar 4-[(5,6-Dimethoxy-1-oxoindan-2-yl)methyl]piperidine120014-30-462 % similar Methyl 1-benzylpiperidine-4-carboxylate10315-06-745 % similar Ethyl 1-(phenylmethyl)-4-piperidinecarboxylate24228-40-841 % similar 4-Amino-1-benzylpiperidine dihydrochloride1205-72-739 % similar Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate hydrochloride52763-21-039 % similar 1-Benzyl-4-oxo-3-piperidinecarboxylic acid methyl ester monohydrochloride3939-01-338 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds

Same formula

Donepezil hydrochloride110119-84-1

Elsewhere

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