chempirical

Glibenclamide

C23H28ClN3O5SCAS 10238-21-8494.00 g/mol

Open in Covalent MOL file
OClOHNSOONHONH
Aryl halideEtherSulfonamide

Properties

Molecular formula
C23H28ClN3O5S
Molar mass
494.00 g/mol
Exact mass
493.1438 Da
Melting point
169 °C
logP
4.42Crippen estimate
Polar surface area
120.6 Ų
H-bond donors / acceptors
3 / 5
Rotatable bonds
8

Identifiers

CAS number
10238-21-8
SMILES
COc1ccc(Cl)cc1C(O)=NCCc1ccc(S(=O)(=O)NC(O)=NC2CCCCC2)cc1
InChIKey
ZNNLBTZKUZBEKO-UHFFFAOYSA-N
InChI
InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)

Weigh it out

Type any one amount. The others follow from the molar mass.

Names and synonyms

109 names · show all
  • Tiabet
  • Orabetic
  • Glitisol
  • Prodiabet
  • Glukovital
  • Glynase
  • Melix
  • Glucal
  • Diaben
  • Norboral
  • Semi-daonil
  • Wuglucon
  • Gl
  • Dia-basan
  • Glucoremed
  • Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-
  • Urea, 1-[[p-[2-(5-chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexyl-
  • 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide
  • 1-[4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulfonyl]-3-cyclohexylurea
  • Glybenzcyclamide
  • Glyburide
  • HB 419
  • N-[4-(β-(2-Methoxy-5-chlorobenzamido)ethyl)benzosulfonyl]-N′-cyclohexylurea
  • 1-[[-p-[2-(5-Chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexylurea
  • U 26452
  • N-4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulfonyl-N′-cyclohexylurea
  • HD 419
  • N-[4-[β-(2-Methoxy-5-chlorobenzamido)ethyl]benzenesulfonyl]-N′-cyclohexylurea
  • Maninil
  • Euglucon 5
  • UR 606
  • 1-[p-2-(5-Chloro-o-anisamido)ethylphenylsulfonyl]-3-cyclohexylurea
  • Daonil
  • Euglucon
  • Gilemal
  • Diabeta
  • Euglucan
  • Euglykon
  • Semi-euglucon N
  • Semi-euglucon
  • Daonil N
  • Glycolande N
  • Betanase
  • Betanaz
  • Micronase
  • Med-glionil
  • Humedia
  • Miglucan
  • Betanese 5
  • Glibens
  • Glucohexal
  • Debtan
  • Antibet
  • Dibelet
  • Glimel
  • Cytagon
  • Glibet
  • Azuglucon
  • Glycomin
  • Glibetic
  • Glucolon
  • Glisulin
  • Glicem
  • Glyben
  • GBN 5
  • Bastiverit
  • Glibesyn
  • Sugril
  • Suraben
  • Gliben
  • Glucoven
  • Libanil
  • Glucomid
  • Gliban
  • Glibenil
  • Hemi-daonil
  • Calabren
  • Benclamin
  • Glamide
  • Glibil
  • Pira
  • Gliboral
  • Glucobene
  • Renabetic
  • Apo-glibenclamide
  • Glimide
  • Glidiabet
  • Gluben
  • Yuglucon
  • Glycolande
  • Duraglucon
  • Gliben-puren N
  • Gluco-tabinen
  • Abbenclamide
  • Adiab
  • Diabiphage
  • Glubate
  • Glimidstada
  • Glibomet
  • RP 1127
  • Glustat
  • Glyform
  • Gluvans
  • Glicuformine
  • Glymet
  • Glyburine
  • 5-Chloro-N-(2-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenyl)ethyl)-2-methoxybenzamide
  • Diazet
  • Amglidia

Work with Glibenclamide

Predict the NMR spectrum1H and 13C shifts with multiplicities Make a solutionWhat to weigh for any molarity and volume Check drug-likenessLipinski, Veber and lead-likeness Isotope patternExact mass and the mass spectrum pattern

Similar compounds

N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-5-chloro-2-methoxybenzamide16673-34-061 % similar Glipizide29094-61-957 % similar Gliquidone33342-05-148 % similar Acetohexamide968-81-047 % similar Chlorpropamid94-20-242 % similar Glimepiride93479-97-141 % similar Tiapride51012-32-939 % similar Tiapride hydrochloride51012-33-037 % similar

Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds

Elsewhere

PubChem CAS Common Chemistry NIST WebBook