Indomethacin
Properties
- Molecular formula
- C19H16ClNO4
- Molar mass
- 357.79 g/mol
- Exact mass
- 357.0768 Da
- Density
- 1.38 g/mL
- Melting point
- 158 °C
- pKa
- 4.5
- Water solubility
- 937 µg/L (25 °C)
- logP
- 3.93Crippen estimate
- Polar surface area
- 68.5 Ų
- H-bond donors / acceptors
- 1 / 3
- Rotatable bonds
- 4
Hazards
Danger
- H300 Fatal if swallowed81% of notifiers
- H301 Toxic if swallowed19% of notifiers
- H317 May cause an allergic skin reaction24.9% of notifiers
- H318 Causes serious eye damage18.5% of notifiers
- H335 May cause respiratory irritation18.5% of notifiers
- H336 May cause drowsiness or dizziness18.5% of notifiers
- H360 May damage fertility or the unborn child25.4% of notifiers
- H373 May causes damage to organs through prolonged or repeated exposure19% of notifiers
- H413 May cause long lasting harmful effects to aquatic life19% of notifiers
Aggregated from 189 ECHA notifications, via PubChem; a share says how many notifiers assign that statement.
Precautionary statements
P203, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P316, P302+P352, P304+P340, P305+P354+P338, P317, P318, P319, P321, P330, P333+P317, P362+P364, P403+P233, P405, P501
Identifiers
CAS number
53-86-1SMILES
COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1InChIKey
CGIGDMFJXJATDK-UHFFFAOYSA-NInChI
InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)Weigh it out
Type any one amount. The others follow from the molar mass and density.
Names and synonyms
84 names · show all
- 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-
- Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
- Amuno
- 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
- 1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid
- α-[1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl]acetic acid
- Indocid
- Indocin
- Indometacin
- Indomethacine
- Metindol
- N-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid
- 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid
- Artrinovo
- Artrivia
- Confortid
- Idomethine
- Inacid
- Indomed
- Indomee
- Infrocin
- Mezolin
- Methazine
- Indacin
- 1-(4-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
- Indomecol
- Metacen
- Metartril
- Dolovin
- Indo-rectolmin
- Reumacide
- Sadoreum
- 1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid
- Indometacine
- 1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid
- Indren
- Inteban
- Chrono-indocid 75
- Dolcidium PL
- Bonidon gel
- Imbrilon
- Indomod
- Indo-phlogont
- Indo-tablinen
- Dolcidium
- Bonidin
- Mobilan
- Indomethine
- Inflazon
- Elmetacin
- Indoxen
- Vonum
- Tannex
- Durametacin
- Indoptic
- Argun
- Mikametan
- Catlep
- Indoptol
- Chrono-indicid
- Lausit
- Rheumacin LA
- Inteban SP
- Chibro-amuno
- Artracin
- Indorektal
- Indocid (pharmaceutical)
- Innamit
- Indonol
- [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
- Vital vitacid
- IndoRich
- Flam
- Globa
- NSC 77541
- Indocollyre
- Endol
- Microcid
- Indocine
- Aconip
- 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
- 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
- IMC
Work with Indomethacin
Similar compounds
Acemetacin53164-05-982 % similar
2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl)ethanone2854-32-269 % similar
5-Methoxy-2-methylindole-3-acetic acid2882-15-750 % similar
7-Methoxy-1-naphthaleneacetic acid6836-22-244 % similar
5-Methoxyindoleacetic acid3471-31-642 % similar
(3-Methoxyphenyl)acetic acid1798-09-041 % similar
2,5-Dimethoxyphenylacetic acid1758-25-441 % similar
2-(2,4-Dimethoxyphenyl)acetic acid6496-89-541 % similar
Tanimoto similarity of circular fingerprints over the whole catalogue. All similar compounds